The insurgents were travelling in two vehicles when they were hit by the air strike in Sara Skhar area of Shawalikot district, said Qasim Azad, secretary of the provincial police.
The militants were heading toward a security checkpoint in bid to seize it, he said.
Separately, 24 Taliban militants were killed in a raid by Afghan forces in central Maidan Wardak province last night, officials said.
The militants targeted were members of Taliban’s special force called ‘Red Unit’. Laser weapons were seized from them.
The operation happened in Buland Kheil, Kamal Kheil and Chopan villages of Jaghatu district.
Three militants were arrested during the operation.