The provincial police commandment said the militants were killed in Haska Mina and Achin districts.
According to the local security officials, at least six of the militants were killed in Kharga area of Haska Mina district while two others were killed in Pekha area of Achin.
The officials further added that the local residents did not suffer any casualties in the airstrikes.
The anti-government armed militant groups have not commented regarding the report so far.
Nangarhar is located in eastern part of Afghanistan and is the only confirmed place in Afghanistan where ISIS militants have foothold.