Tariq Arian, a spokesman for the Interior Ministry said that the explosion took place at around 7:25 p.m. in Wazir Akbar Khan mosque while people were gathered for evening prayers.
Mohammad Ayaz Niazi, imam of the mosque also lost his life in the attack, the official added.
All the injured individuals have been taken to hospital.
According to the ministry, police defused another bomb at the attack scene.
Meanwhile, the Presidential Palace condemned the “terror attack,” saying attacks on mosques, hospitals, and other civilian sites are anti-humanitarian act.