Officials in Kabul Police Headquarters confirmed the incident and said the wife of Senator Shamil was also killed in the incident.
The officials further added that the shooting took place at around 3am local time in the vicinity of 4th police district of the city.
Circumstances surrounding the shooting incident have not been ascertained so far with the security officials saying the incident may have links with the family feud.
A spokesman for Kabul Police Commandment Ferdaws Faramrz has said the 12 security guards of the Senator were present in his residence when the incident took place.
Mr. Shamil was representing the North-eastern Takhar province in the Upper House of the Parliament, Meshrano Jirga (Senate House).