She is expected to meet Pakistani Prime Minister Nawaz Sharif, Adviser on National Security and Foreign Affairs Sartaj Aziz and Chief of Army Staff General Raheel Sharif.
An official said that bilateral relations, regional security situation and the intensifying tensions between Pakistan and India are likely to come under discussion. She would be accompanied by a high-level delegation.
Rice will meet Army Chief General Raheel Sharif at the Pakistan Army General Headquarters Rawalpindi.
Earlier this month, she also telephoned Afghan President Ashraf Ghani and assured him that the United States and their international partners were committed to the Afghan government of national unity in its efforts to achieve a stable, secure, and prosperous Afghanistan.
The US has expressed concern over recent developments and rising tensions between Islamabad and New Delhi mainly caused by the continuing ceasefire violations along the Line of Control and Working Boundary between the two countries.
Washington has reiterated its call for Pakistan and India to resume dialogue to resolve issues, and said America wanted to see tensions decrease between the two countries.
Pakistan’s Prime Minister Sharif is expected to meet US President Barack Obama in Washington in October.
Pakistan faced the largest number of civilian casualties with nine dead and several dozens injured in the Indian firing on Thursday, hyping the tensions. Islamabad has repeatedly summoned the Indian diplomat in Pakistan to hand over protests for the ceasefire violations.
In a separate development, the US department of defence has awarded a $57 million contract to Bell Helicopter to provide Ah-1Z Viper attack helicopters to Pakistan.
The deal is part of a larger $581 million contract, most of which goes to the US Navy.
The contract covers the manufacture and delivery of 15 Lot 12 UH-1Y Venom utility helicopters, 19 Lot 12 AH-1Zs, one Lot 13 UH-1Y, and 21 auxiliary fuel kits for the government of Pakistan. Some of these initial helicopters will be delivered by the end of August 2018.