The explosion took place at about 9.45am local time close to Habibia High School and the target appeared to have been a Hilux vehicle.
According to eyewitnesses, the explosion had been from a roadside mine and caused casualties.
Some eyewitnesses said the Hilux vehicle was being driven by IE forces at the time of the explosion.
According to eyewitnesses at least five people were wounded in the explosion including IE forces.
Immediately after the explosion, IE forces cordoned off the area, and ambulances were seen arriving at the scene.
So far no group has claimed responsibility for the explosion but ISIS affiliates in Afghanistan (ISIS-K), known locally as Daesh, have been responsible for a number of explosions in Kabul in recent months.